截止目前,联川生物公司全球microRNA微阵列芯片客户发表论文已突破200篇,升至212篇。其中在国际顶级期刊《Cell》,《Nature》,《Science》上累计发表权威性论文8篇。来自中国科学院,清华大学,北京大学,浙江大学,复旦大学,同济大学,武汉大学,中山大学等知名科研机构和高校的研究团队使用我们的微阵列芯片平台已累计发表高影响力论文38篇。
公司microRNA芯片客户的研究领域已涵盖包括干细胞研究,癌症研究,神经系统科学,心血管研究,免疫学,生殖生物学,植物科学,病毒学,和small RNA发现等众多miRNA热点研究方向。
联川生物公司提供的一站式miRNA芯片表达谱检测服务,基于创新的**µParaflo®微流体微阵列平台,原位合成探针,并与Sanger miRBase同步更新(最新版本为16.0),全力为国内科研人员提供高效可靠的miRNA表达谱检测分析服务。
以下为国内研究团队发表的部分microRNA研究文章
1. Wang, R., Wang, Z. X., Yang, J. S., Pan, X., De, W. and Chen, L. B. (2011). MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). Oncogene.[abstract] 2. Li, Y., Wang, F., Xu, J., Ye, F., Shen, Y., Zhou, J., Lu, W., Wan, X., Ma, D. and Xie, X. (2011). Progressive miRNA expression profiles in cervical carcinogenesis and identification of HPV related target genes for miR-29. J. Pathol. [abstract] 3. Zhu Y, Yu X, Fu H, Wang H, Wang P, Zheng X, Wang Y. (2010) MicroRNA-21 is involved in ionizing radiation-promoted liver carcinogenesis. Int J Clin Exp Med 3(3), 211-22. [abstract] 4. Ding L, Xu Y, Zhang W, Deng Y, Si M, Du Y, Yao H, Liu X, Ke Y, Si J, Zhou T. (2010) MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. Cell Res 20(7), 784-93. [abstract] 5. Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, Hoang T, Xu X, Mi QS, Xin M, Wang F, Appel B, Lu QR. (2010) MicroRNA-mediated control of oligodendrocyte differentiation. Neuron 65(5), 612-26. [abstract] 6. Yuan Y, Wang JY, Xu LY, Cai R, Chen Z, Luo BY. (2010) MicroRNA expression changes in the hippocampi of rats subjected to global ischemia. J Clin Neurosci [Epub ahead of print] [abstract] 7. Cheng Y, Zhu P, Yang J, Liu X, Dong S, Wang X, Chun B, Zhuang J, Zhang C. (2010) Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4. Cardiovasc Res [Epub ahead of print]. [abstract] 8. Zou J, Li WQ, Li Q, Li XQ, Zhang JT, Liu GQ, Chen J, Qiu XX, Tian FJ, Wang ZZ, Zhu N, Qin YW, Shen B, Liu TX, Jing Q. (2010) Two Functional MicroRNA-126s Repress a Novel Target Gene p21-Activated Kinase 1 to Regulate Vascular Integrity in Zebrafish. Circ Res [Epub ahead of print]. [abstract] 9. Zhou X, Zuo Z, Zhou F, Zhao W, Sakaguchi Y, Suzuki T, Suzuki T, Cheng H, Zhou R. (2010) Profiling Sex-specific piRNAs in Zebrafish. Genetics 186(4), 1175-85. [abstract] 10. Qin X, Wang X, Wang Y, Tang Z, Cui Q, Xi J, J Li YS, Chien S, Wang N. (2010) MicroRNA 11. Lv DK, Bai X, Li Y, Ding XD, Ge Y, Cai H, Ji W, Wu N, Zhu YM. (2010) Profiling of cold-stress-responsive miRNAs in rice by microarrays. Gene [Epub ahead of print] 12. Zhang Z, Yu J, Li D, Zhang Z, Liu F, Zhou X, Wang T, Ling Y, Su Z. (2009) PMRD: plant microRNA database. Nucleic Acids Res [Epub ahead of print] [abstract] 13. Meng Y, Huang F, Shi Q, Cao J, Chen D, Zhang J, Ni J, Wu P, Chen M. (2009) Genome-wide survey of rice microRNAs and microRNA-target pairs in the root of a novel auxin-resistant mutant. Planta [Epub ahead of print]. [abstract] 14. Ting Chen, Zhouqing Huang, Liansheng Wang, Yue Wang, Feizhen Wu, Shu Meng, Changqian Wang. (2009) MicroRNA
15. Hou J, Wang P, Lin L, Liu X, Ma F, An H, Wang Z, Cao X. (2009) MicroRNA