KLK4 (Center) Peptide
产品名称： KLK4 (Center) Peptide
英文名称： KLK4 (Center) Peptide
产品编号： P1970
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of KLK4.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human KLK4.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta.
Hart PS, Hart TC, Michalec MD, Ryu OH, Simmons D, Hong S, Wright JT.J Med Genet. 2004 Jul;41(7):545-9.
- 2.
- Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer.
Xi Z, Klokk TI, Korkmaz K, Kurys P, Elbi C, Risberg B, Danielsen H, Loda M, Saatcioglu F.Cancer Res. 2004 Apr 1;64(7):2365-70.
- 3.
- Identification of naturally processed CD4 T cell epitopes from the prostate-specific antigen kallikrein 4 using peptide-based in vitro stimulation.
Hural JA, Friedman RS, McNabb A, Steen SS, Henderson RA, Kalos M.J Immunol. 2002 Jul 1;169(1):557-65.
- Entrez GeneID:
- 9622
- Protein Accession#:
- NP_004908;Q9Y5K2
- Gene Name:
- KLK4
- Gene Alias:
- ARM1,EMSP,EMSP1,KLK-L1,MGC116827,MGC116828,PROSTASE,PRSS17,PSTS
- Gene Description:
- kallikrein-related peptidase 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- androgen-regulated message 1,enamel matrix serine protease 1,kallikrein 4 (prostase, enamel matrix, prostate),kallikrein-like protein 1,protease, serine, 17