Chromatrap Native ChIP kits provide an alternative to traditional cross-linked ChIP, which removes the need for fixing cells prior to extraction.

Performing ChIP with native chromatin enables users to gain insights to histone and certain abundant transcription factors that are likely to be naturally bound to DNA. The Chromatrap Native ChIP kits provide a quicker, easier and more efficient way of performing ChIP assays from native chromatin. The bead-free technology maximizes maximises the capture efficiency with high resolution.

Advantages of Native ChIP Kit

ChIP in under 5 hours
User friendly due to less manual handling steps
Significantly reduced sample loss between steps
No background due to bead-free filter technology
Specifics

ChIP from as little as 1000 cells or 50ng of DNA
Wide dynamic range for low (50ng) and high (50ug) chromatin loadings.
Perfect for transcription factors (low and abundant), DNA-associated histone modifications
Compatible for downstream qPCR and NGS