FITC标记的单纯疱疹病毒糖蛋白D抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的单纯疱疹病毒糖蛋白D抗体

FITC标记的单纯疱疹病毒糖蛋白D抗体

商家询价

产品名称： FITC标记的单纯疱疹病毒糖蛋白D抗体

英文名称： Anti-HSV1 gD/FITC

产品编号： HZ-18094R-FITC

产品价格： null

产品产地： 中国/上海

品牌商标： HZbscience

更新时间： 2023-08-17T10:24:20

使用范围： ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749 点击查看
  • 传真 : 点击查看
  • 邮箱 : www.shzbio.net
  • 二维码 : 点击查看
进入展台

 Rabbit Anti-HSV1 gD/FITC Conjugated antibody 

FITC标记的单纯疱疹病毒糖蛋白D抗体

 

文名称 Anti-HSV1 gD/FITC
中文名称 FITC标记的单纯疱疹病毒糖蛋白D抗体
别    名 GD; Glycoprotein D; GD_HHV1A; Herpes simplex virus type 1 glycoprotein D; HSV1 glycoprotein D; US6.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细菌及病毒  糖蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Herpes simplex virus
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSV1 gD, strain Angelotti
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.

Function:
Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM, PVRL1 and 3-O-sulfated heparin sulfate. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity). {ECO:0000250}.

Subunit:
Homodimer (By similarity). Interacts with host receptor TNFRSF14. Interacts with host receptor PVRL1. Interacts (via profusion domain) with gB; this interaction occurs in the absence of gH/gL. Interacts (via profusion domain) with gH/gL heterodimer; this interaction occurs in the absence of gB. Associates with the gB-gH/gL-gD complex. Interacts (via C-terminus) with UL11 tegument protein (By similarity). {ECO:0000250}.

Subcellular Location:
Virion membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. {ECO:0000250}. 

Similarity:
Belongs to the herpesviridae glycoprotein D family. 

Database links:
 UniProtKB/Swiss-Prot: Q15431.2


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

单纯疱疹病毒1型（HSV-1）属于包括HSV-2、Epstein Barr病毒（EBV）和Varicella zoster（水痘）病毒在内的一个家族。HSV-1和HSV-2极难区分。这个家族的成员具有特征的病毒粒子结构。双链DNA基因组包含在二十面体衣壳内，包埋在蛋白质层（TEGUTIDES）中，并被来自最后宿主的核膜的脂质包膜包围，其被病毒特异性糖蛋白穗修饰。这些病毒能够进入潜伏期，宿主没有明显的感染迹象，感染剂的水平变得非常低。在潜伏期，病毒DNA整合到宿主细胞的基因组中。Glycoprotein D（GD）与细胞受体结合有助于病毒侵入细胞。单纯疱疹病毒1型（HSV-1）糖蛋白D（GD）是进入病毒的重要组成部分，它负责病毒的渗透和随后的细胞-细胞扩散。