IRF1 (Human) Recombinant Protein (P01)
产品名称： IRF1 (Human) Recombinant Protein (P01)
英文名称： IRF1 (Human) Recombinant Protein (P01)
产品编号： H00003659-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human IRF1 full-length ORF ( NP_002189.1, 1 a.a. - 325 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP
- Theoretical MW (kDa):
- 61.38
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Histone deacetylase-1 is enriched at the platelet-derived growth factor-D promoter in response to interleukin-1beta and forms a cytokine-inducible gene-silencing complex with NF-kappab p65 and interferon regulatory factor-1.
Liu MY, Khachigian LM.J Biol Chem. 2009 Dec 11;284(50):35101-12. Epub 2009 Oct 20.
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3659
- GeneBank Accession#:
- NM_002198.1
- Protein Accession#:
- NP_002189.1
- Gene Name:
- IRF1
- Gene Alias:
- IRF-1,MAR
- Gene Description:
- interferon regulatory factor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq
- Other Designations:
- interferon regulatory factor-1
- Related Disease
- Acute Disease
- Arthritis, Juvenile Rheumatoid
- Asthma
- Asthma
- Behcet Syndrome
- Breast cancer
- Breast Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Celiac Disease
- Crohn Disease
- Crohn's disease
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Graves Disease
- Hepatitis B