FOLR2,胎盘叶酸受体蛋白2抗体

产品编号HZ-9595R
英文名称FOLR2
中文名称胎盘叶酸受体蛋白2抗体
别 名fetal/placental; Folbp 2; beta hFR; FBP; FBP/PL 1; FBP2; folate receptor 2 (fetal); Folate receptor 2; Folate receptor; Folate receptor beta; Folate receptor, fetal/placental; Folbp2; Folr2; FOLR2_HUMAN; FR beta; FR P3; FR-beta; Placental folate binding protein; Placental folate-binding protein.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 细胞膜受体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Horse,
FOLR2,胎盘叶酸受体蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量25kDa
细胞定位细胞膜 分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Folate receptor (101-200aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FOLR2,胎盘叶酸受体蛋白2抗体PubMedPubMed
产品介绍background:
Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydofolate into the cell.

Function:
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.

Subcellular Location:
Cell membrane. Secreted.

Tissue Specificity:
Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.

Post-translational modifications:
Eight disulfide bonds are present.
N-glycosylated.

Similarity:
Belongs to the folate receptor family.

Database links:
Entrez Gene: 2350 Human
Entrez Gene: 293154 Rat
Omim: 136425 Human
SwissProt: P14207 Human
Unigene: 433159 Human
Unigene: 8801 Rat

FOLR2,胎盘叶酸受体蛋白2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.