TLR5 polyclonal antibody
产品名称： TLR5 polyclonal antibody
英文名称： TLR5 polyclonal antibody
产品编号： PAB14602
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TLR5.
- Immunogen:
- A synthetic peptide corresponding to amino acids 151-181 of human TLR5.
- Sequence:
- CDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQ
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.
Chuang T, Ulevitch RJ.Biochim Biophys Acta. 2001 Mar 19;1518(1-2):157-61.
- 2.
- The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6).
Muzio M, Natoli G, Saccani S, Levrero M, Mantovani A.J Exp Med. 1998 Jun 15;187(12):2097-101.
- 3.
- Innate immunity: the virtues of a nonclonal system of recognition.
Medzhitov R, Janeway CA Jr.Cell. 1997 Oct 31;91(3):295-8.
- Application Image
- ELISA
- Entrez GeneID:
- 7100
- Protein Accession#:
- NP_003259
- Gene Name:
- TLR5
- Gene Alias:
- FLJ10052,MGC126430,MGC126431,SLEB1,TIL3
- Gene Description:
- toll-like receptor 5
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq
- Other Designations:
- OTTHUMP00000036039,Toll/interleukin-1 receptor-like protein 3
- Related Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bacteriuria
- Bronchiolitis Obliterans
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Chagas Cardiomyopathy
- Chorioamnionitis
- Chronic Disease
- Crohn Disease
- Crohn's disease
- Cystic Fibrosis
- Cystitis
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Duodenal Ulcer
- Edema
- Fetal Membranes, Premature Rupture