FITC标记的锚蛋白重复及SAM结构域蛋白6抗体
产品名称： FITC标记的锚蛋白重复及SAM结构域蛋白6抗体
英文名称： Anti-ANKS6/FITC
产品编号： HZ-9099R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-ANKS6/FITC Conjugated antibody
FITC标记的锚蛋白重复及SAM结构域蛋白6抗体
| 产品编号 | bs-9099R-FITC |
| 英文名称 | Anti-ANKS6/FITC |
| 中文名称 | FITC标记的锚蛋白重复及SAM结构域蛋白6抗体 |
| 别 名 | ANKRD14; Anks6; ANKS6_HUMAN; ankyrin repeat and SAM domain containing protein 6; Ankyrin repeat and SAM domain-containing protein 6; ankyrin repeat domain 14; ankyrin repeat domain containing protein 14; Ankyrin repeat domain-containing protein 14; SAM domain containing protein 6; SAM domain-containing protein 6; SamCystin; SAMD6; sterile alpha motif domain containing 6; sterile alpha motif domain containing protein 6; Sterile alpha motif domain-containing protein 6. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 92kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANKS6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ANKS6, also known as ankyrin repeat domain-containing protein 14, SAMD6 (sterile alpha motif domain-containing protein 6), SamCystin or PKDR1, is an 871 amino acid phosphoprotein that contains eleven ANK repeats, one SAM domain and exists as three alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 9q22.33, ANKS6 is necessary for renal function and is linked to renal cyst formation in polycystic kidney disease. ANKS6 interacts with BICC1, another protein linked to polycystic kidney disease, and both co-localize to the same cell region. ANKS6 is involved in protein–protein interactions with both itself as well as BICC1, and both proteins function in a molecular pathway that is linked to cystogenesis. ANKS6 may also be associated with dental anomolies. Function: Required for renal function (By similarity). Similarity: Contains 11 ANK repeats. Contains 1 SAM (sterile alpha motif) domain. Database links: UniProtKB/Swiss-Prot: Q68DC2.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
AKS6，也称为锚蛋白重复结构域包含蛋白14，SAMD6（无菌α基结构域包含蛋白6），SamCystin或PKDR1，是包含十一个氨基酸重复序列的871个氨基酸磷酸化蛋白，一个山姆结构域，并作为三个交替剪接的亚型存在。由一个基因映射到人类染色体9q22.33，ANKS6是必要的肾功能，并与肾囊肿形成多囊肾病。AKS6与BiC1相互作用，BICC1是与多囊肾病相关的另一种蛋白，两者共同定位到同一细胞区域。AKS6参与了蛋白自身与BICC1的相互作用，这两种蛋白在与细胞发生相关的分子通路中起作用。AKS6也可能与牙齿异常有关。