RNF14,环指蛋白14抗体

产品编号HZ-9159R
英文名称RNF14
中文名称环指蛋白14抗体
别 名Androgen receptor associated protein 54; Androgen receptor-associated protein 54; ARA 54; ARA54; E3 ubiquitin protein ligase RNF14; E3 ubiquitin-protein ligase RNF14; HFB 30; HFB30; HRIHFB2038; RING finger protein 14; RNF 14; Rnf14; RNF14_HUMAN; TRIAD 2; TRIAD2; Triad2 protein.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 染色质和核信号 信号转导 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
RNF14,环指蛋白14抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量54kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human RNF14
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
RNF14,环指蛋白14抗体PubMedPubMed
产品介绍background:
Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.

Function:
Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.

Subunit:
Interacts with the ubiquitin-conjugating enzymes UBE2E1 and UBE2E2. Interacts with AR/androgen receptor; testosterone- and RNF6-regulated it promotes AR transcriptional activity.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination.

RNF14,环指蛋白14抗体Similarity:
Belongs to the RBR family. RNF14 subfamily.
Contains 1 IBR-type zinc finger.
Contains 2 RING-type zinc fingers.
Contains 1 RWD domain.

Gene ID:
9604

Database links:
Entrez Gene: 9604 Human
Entrez Gene: 56736 Mouse
Entrez Gene: 619577 Rat
Omim: 605675 Human
SwissProt: Q9UBS8 Human
SwissProt: Q9JI90 Mouse
Unigene: 483616 Human
Unigene: 228903 Mouse
Unigene: 115357 Rat

RNF14,环指蛋白14抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.