FITC标记的真核翻译起始因子2C4抗体
产品名称: FITC标记的真核翻译起始因子2C4抗体
英文名称: Anti-Argonaute 4/FITC
产品编号: HZ-12518R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Argonaute 4/FITC Conjugated antibody
FITC标记的真核翻译起始因子2C4抗体
英文名称 | Anti-Argonaute 4/FITC |
中文名称 | FITC标记的真核翻译起始因子2C4抗体 |
别 名 | eIF2C4; 5730550L01Rik; Ago 4; Ago4; AGO4_HUMAN; Argonaute4; EIF 2C 4; eIF-2C 4; eIF2C 4; Eif2c4; eukaryotic translation initiation factor 2C 4; eukaryotic translation initiation factor 2C; hAgo4; KIAA1567; Piwi/Argonaute family protein meIF2C4; Protein argonaute-4. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 97kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Argonaute 4/eIF2C4 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic containing PAZ and PIWI domains, and it may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and eukaryotic translation initiation factor 2C, 1. [provided by RefSeq, Jul 2008] Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Subunit: Interacts with EIF4B, IMP8, PRMT5, TNRC6A and TNRC6B. Subcellular Location: Cytoplasm. Similarity: Belongs to the argonaute family. Ago subfamily. Contains 1 PAZ domain. Contains 1 Piwi domain.Cellular localization. Database links: Entrez Gene: 192670 Human Entrez Gene: 76850 Mouse Entrez Gene: 298533 Rat Omim: 607356 Human SwissProt: Q9HCK5 Human SwissProt: Q8CJF8 Mouse Unigene: 471492 Human Unigene: 86705 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码Argonaute家族成员,它们在RNA干扰中起作用。该编码蛋白具有高度碱性,含有PAZ和PIWI结构域,可能参与短干扰RNA介导的基因沉默。该基因位于包括argonaute 3和真核翻译起始因子2C,1在内的一系列紧密相关的家族成员的染色体1上。[ RefSeq,JUL 2008 ]