ABAT (Human) Recombinant Protein (P01)
产品名称： ABAT (Human) Recombinant Protein (P01)
英文名称： ABAT (Human) Recombinant Protein (P01)
产品编号： H00000018-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human ABAT full-length ORF ( AAH08990, 1 a.a. - 116 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MENHHSPKGQRRFQRKGVIGAVFCRMSQSSPSRQGKEGCCREGTAYAKAYQFMASHLSLGKPVSTGSIPRFNKALFNKQAKCKPNHYSFIGLSMLSPENFSIGCKYSVWFSETKGF
- Theoretical MW (kDa):
- 38.5
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 18
- GeneBank Accession#:
- BC008990
- Protein Accession#:
- AAH08990
- Gene Name:
- ABAT
- Gene Alias:
- FLJ17813,GABA-AT,GABAT,NPD009
- Gene Description:
- 4-aminobutyrate aminotransferase
- Omim ID:
- 137150
- Gene Ontology:
- Hyperlink
- Gene Summary:
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq
- Other Designations:
- GABA aminotransferase,GABA transferase,gamma-amino-N-butyrate transaminase