TRIB2 (Human) Recombinant Protein (Q01)
产品名称: TRIB2 (Human) Recombinant Protein (Q01)
英文名称: TRIB2 (Human) Recombinant Protein (Q01)
产品编号: H00028951-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Human TRIB2 partial ORF ( NP_067675, 254 a.a. - 343 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- FHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
- Theoretical MW (kDa):
- 35.64
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 28951
- GeneBank Accession#:
- NM_021643
- Protein Accession#:
- NP_067675
- Gene Name:
- TRIB2
- Gene Alias:
- C5FW,GS3955,TRB2
- Gene Description:
- tribbles homolog 2 (Drosophila)
- Omim ID:
- 609462
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
- Other Designations:
- tribbles homolog 2
- Related Disease