产品概述：Recombinant protein of human CD3e molecule, epsilon (CD3-TCR complex) (CD3E), expressed in human cells

蛋白长度：A DNA sequence from GoldORF clone, [GH38144V], encoding the extracellular domain (Asp23-Asp126) of human CD3E

表达系统：HEK293

种属：Human

标签类型：C-DDK/His

分子量：14 kDa

通用名：CD3E

总结：The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, pH7.4, 10% glycerol

别名：IMD18; T3E; TCRE