CDC40,细胞分裂周期同源蛋白40抗体

产品编号HZ-4295R
英文名称CDC40
中文名称细胞分裂周期同源蛋白40抗体
别 名Cell division cycle 40 homolog; EH binding protein 3; Ehb3; Pre mRNA processing factor 17; PRP17; PRP17 homolog; PRPF17.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 染色质和核信号 细胞周期蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
CDC40,细胞分裂周期同源蛋白40抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量64kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CDC40
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CDC40,细胞分裂周期同源蛋白40抗体PubMedPubMed
产品介绍background:
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]

Function:
Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.

Subunit:
Identified in the spliceosome C complex.

Subcellular Location:
Nucleus.

Similarity:
Contains 7 WD repeats.

CDC40,细胞分裂周期同源蛋白40抗体Database links:
Entrez Gene: 51362 Human
Entrez Gene: 71713 Mouse
Entrez Gene: 361859 Rat
Omim: 605585 Human
SwissProt: O60508 Human
SwissProt: Q9DC48 Mouse
Unigene: 428147 Human
Unigene: 46063 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.