FITC标记的FBG4蛋白抗体
产品名称： FITC标记的FBG4蛋白抗体
英文名称： Anti-FBG4/FITC
产品编号： HZ-16031R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FBG4/FITC Conjugated antibody
FITC标记的FBG4蛋白抗体
| 英文名称 | Anti-FBG4/FITC |
| 中文名称 | FITC标记的FBG4蛋白抗体 |
| 别 名 | F box only protein 17; F box only protein 26; F-box only protein 17; F-box only protein 26; F-box protein 17; F-box protein FBG4; FBX17; FBX17_HUMAN; FBX26; Fbxo17; FBXO26; FLJ11798; FLJ25205; FLJ58300; MGC9379. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FBG4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins. Tissue Specificity: Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain. Similarity: Contains 1 F-box domain. Contains 1 FBA (F-box associated) domain. Database links: Entrez Gene: 115290 Human Entrez Gene: 50760 Mouse Entrez Gene: 292757 Rat GenBank: NM_024907 Human GenBank: NM_148169 Human GenBank: NM_015796 Mouse Omim: 609094 Human SwissProt: Q96EF6 Human SwissProt: Q9QZM8 Mouse SwissProt: Q6AY27 Rat Unigene: 531770 Human Unigene: 358659 Mouse Unigene: 53606 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的F盒蛋白家族的成员，其特征在于F盒基序。F-box蛋白构成泛素蛋白连接酶复合物SCF(SKP1-cullin-F-box)的四个亚基之一，SCFs在磷酸化依赖性泛素化中起作用。F-box蛋白分为3类：含有WD-40结构域的Fbws，含有富含亮氨酸重复序列的Fbls，以及含有不同蛋白质-蛋白质相互作用模块或没有可识别基序的Fbxs。该基因编码的蛋白属于FBXS类，含有F盒结构域。选择性剪接导致多个转录变体。[ RefSeq，JUL 2013 ]