FITC标记的T淋巴细胞转运蛋白1抗体
产品名称： FITC标记的T淋巴细胞转运蛋白1抗体
英文名称： Anti-LMO1/FITC
产品编号： HZ-18313R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LMO1/FITC Conjugated antibody
FITC标记的T淋巴细胞转运蛋白1抗体
| 英文名称 | Anti-LMO1/FITC |
| 中文名称 | FITC标记的T淋巴细胞转运蛋白1抗体 |
| 别 名 | Cysteine rich protein TTG 1; Cysteine rich protein TTG1; LIM domain only 1; LIM domain only protein 1; LMO 1; MGC116692; RBTN 1; RBTN1; RHOM 1; RHOM1; Rhombotin 1; Rhombotin1; T cell translocation protein 1; TTG 1; TTG1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转运蛋白 淋巴细胞 t-淋巴细胞 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Zebrafish, Guinea Pig, Monkey, Cat, Spider Monkey |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 18kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LMO1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012] Function: May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors. Subcellular Location: Nuclear Tissue Specificity: Expressed mainly in the central nervous. Low level of expression in other tissues including thymus. DISEASE: A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD. Similarity: Contains 2 LIM zinc-binding domains. Database links: Entrez Gene: 27152 Cow Entrez Gene: 4004 Human Entrez Gene: 109594 Mouse Entrez Gene: 245979 Rat Entrez Gene: 280646 Zebrafish Omim: 186921 Human SwissProt: Q0P5B3 Cow SwissProt: P25800 Human SwissProt: Q924W9 Mouse SwissProt: Q8JFQ2 Zebrafish Unigene: 654426 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该位点编码含有两个富含半胱氨酸的LIM结构域的转录调节器，但缺少DNA结合结构域。LIM结构域可能在蛋白质相互作用中起作用，因此编码的蛋白质可以通过竞争性结合特定的DNA结合转录因子来调节转录。该位点的改变与急性淋巴细胞性T细胞白血病有关。在该位点和至少两个位点、T细胞抗原受体基因的δ亚单位和LIM结构域结合1基因之间观察到染色体重排。另外，已经描述了剪接转录变体。[ RefSeq，JUL 2012 ]