GCH1 (Human) Recombinant Protein (Q01)-蛋白质/抗原/多肽-试剂-生物在线
亚诺法生技股份有限公司（Abnova)
GCH1 (Human) Recombinant Protein (Q01)

GCH1 (Human) Recombinant Protein (Q01)

商家询价

产品名称： GCH1 (Human) Recombinant Protein (Q01)

英文名称： GCH1 (Human) Recombinant Protein (Q01)

产品编号： H00002643-Q01

产品价格： 0

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围： null

亚诺法生技股份有限公司（Abnova)
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进入展台

  • Specification
  • Product Description:
  • Human GCH1 partial ORF ( NP_000152, 84 a.a. - 172 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • ENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIV
  • Theoretical MW (kDa):
  • 35.53
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00002643-Q01
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 2643
  • Gene Name:
  • GCH1
  • Gene Alias:
  • DYT14,DYT5,GCH,GTP-CH-1,GTPCH1
  • Gene Description:
  • GTP cyclohydrolase 1
  • Gene Summary:
  • This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq
  • Other Designations:
  • guanosine 5'-triphosphate cyclohydrolase I

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