ASTN2,星形肌动蛋白抗体

产品编号HZ-11072R
英文名称ASTN2
中文名称星形肌动蛋白抗体
别 名Astn2; Astn-2; Astn 2; ASTN2_HUMAN; Astrotactin 2; Astrotactin2; Astrotactin-2; bA67K19.1; KIAA0634.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow,
ASTN2,星形肌动蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量143kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ASTN2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ASTN2,星形肌动蛋白抗体PubMedPubMed
产品介绍background:
Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.

Subcellular Location:
Membrane.

Similarity:
Belongs to the astrotactin family.
Contains 3 EGF-like domains.
Contains 1 fibronectin type-III domain.

ASTN2,星形肌动蛋白抗体Database links:
UniProtKB/Swiss-Prot: O75129.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.