TLR5 monoclonal antibody (M10), clone 4D12
产品名称： TLR5 monoclonal antibody (M10), clone 4D12
英文名称： TLR5 monoclonal antibody (M10), clone 4D12
产品编号： H00007100-M10
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant TLR5.
- Immunogen:
- TLR5 (NP_003259.2, 351 a.a. ~ 450 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHL
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- TLR5 monoclonal antibody (M10), clone 4D12. Western Blot analysis of TLR5 expression in FHs 173 WE.
- Protocol Download
- Entrez GeneID:
- 7100
- GeneBank Accession#:
- NM_003268
- Protein Accession#:
- NP_003259.2
- Gene Name:
- TLR5
- Gene Alias:
- FLJ10052,MGC126430,MGC126431,SLEB1,TIL3
- Gene Description:
- toll-like receptor 5
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq
- Other Designations:
- OTTHUMP00000036039,Toll/interleukin-1 receptor-like protein 3
- Related Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bacteriuria
- Bronchiolitis Obliterans
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Chagas Cardiomyopathy
- Chorioamnionitis
- Chronic Disease
- Crohn Disease
- Crohn's disease
- Cystic Fibrosis
- Cystitis
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Duodenal Ulcer
- Edema
- Fetal Membranes, Premature Rupture