IGFBP3 (Human) Recombinant Protein
产品名称: IGFBP3 (Human) Recombinant Protein
英文名称: IGFBP3 (Human) Recombinant Protein
产品编号: P4128
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human IGFBP3 (P17936, 264 amino acids) partial recombinant protein expressed in Escherichia coli.
- Theoretical MW (kDa):
- 28.8
- Form:
- Lyophilized
- Preparation Method:
- Escherichia coli expression system
- Purity:
- ≥ 98% by SDS-PAGE and HPLC
- Endotoxin Level:
- < 0.1 ng/ug
- Activity:
- The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is < 0.2 mg/mL, in the presence of 15 ng/mL of human IGF-II.
- Storage Buffer:
- Lyophilized from 20 mM HCl
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with sterilized water, store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 3486
- Protein Accession#:
- P17936
- Gene Name:
- IGFBP3
- Gene Alias:
- BP-53,IBP3
- Gene Description:
- insulin-like growth factor binding protein 3
- Omim ID:
- 146732
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- IGF-binding protein 3,acid stable subunit of the 140 K IGF complex,binding protein 29,binding protein 53,growth hormone-dependent binding protein
- Gene Pathway
- Related Disease
- Abortion, Spontaneous
- Adenocarcinoma
- Adenoma
- Alzheimer Disease
- Alzheimer disease
- Anorexia Nervosa
- Anoxia
- Atherosclerosis
- Barrett Esophagus
- Brain Ischemia
- Brain Neoplasms
- Breast cancer
- Breast Diseases
- Breast Neoplasms
- Bulimia
- Calcinosis
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell