Mycobacterium tuberculosis Ag85B,结核分枝杆菌抗体

产品编号HZ-9268R
英文名称Mycobacterium tuberculosis Ag85B
中文名称结核分枝杆菌抗体
别 名Antigen 85 complex B; 30 kDa extracellular protein; Mycobacterium; Mycolyl transferase 85B; fbpB; Antigen 85-B; 85B; Ag85B; Extracellular alpha-antigen; Fibronectin-binding protein B; Rv1886c; MT1934; MTCY180.32.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 细菌及病毒
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Mycobacteriumtuberculosis
Mycobacterium tuberculosis Ag85B,结核分枝杆菌抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量31kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Ag85B (286-325aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Mycobacterium tuberculosis Ag85B,结核分枝杆菌抗体PubMedPubMed
产品介绍background:
Antigen 85B is the most abundant protein expressed by Mycobacterium tuberculosis (about one quarter). It is a myocolyc transferase in the myc pathway and catalyses - like Ag85A and Ag85C - the transfer of the fatty acid mycolate from one trehalose monomycolate to another, resulting in trehalose dimycolate and free trehalose and helping build the cell wall.

Function:
Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.

Subcellular Location:
Secreted.

Similarity:
Belongs to the mycobacterial A85 antigen family.

Mycobacterium tuberculosis Ag85B,结核分枝杆菌抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.