PEX5抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
PEX5抗体

PEX5抗体

商家询价

产品名称： PEX5抗体

英文名称： PEX5Antibody

产品编号： XY12545-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 PEX5抗体Applications

In-house applications ELISA, WB, IP, IHC, FC     Application not tested? Please see our Guarantee.
Published applications IF, WB Publications 3 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 12545-1-AP;human brain tissuehuman brain tissue were subjected to SDS PAGE followed by western blot with 12545-1-AP(PEX5 antibody) at dilution of 1:500
  • 12545-1-AP;mouse kidney tissueIP Result of anti-PEX5 (IP:12545-1-AP, 4ug; Detection:12545-1-AP 1:500) with mouse kidney tissue lysate 4000ug.
  • 12545-1-AP;human kidney tissueImmunohistochemistry of paraffin-embedded human kidney tissue slide using 12545-1-AP( PEX5 Antibody) at dilution of 1:200 (under 10x lens)
  • 12545-1-AP;human kidney tissueImmunohistochemistry of paraffin-embedded human kidney tissue slide using 12545-1-AP( PEX5 Antibody) at dilution of 1:200 (under 40x lens)
  • 12545-1-AP;HEK-293 cells1X10^6 HEK-293 cells were stained with 0.2ug PEX5 antibody (12545-1-AP, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
Positive WB detected in Human brain tissue, human kidney tissue, L02 cells, mouse brain tissue, mouse kidney tissue
Positive IP detected in Mouse kidney tissue
Positive IHC detected in Human kidney tissue
Positive FC detected in HEK-293 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:100-1:400
 PEX5抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen PEX5 fusion protein ag3268 Full name Peroxisomal biogenesis factor 5
Calculated molecular
weight		 631aa,70 kDa Observed molecular 
weight		 80 kDa
GenBank accession 
number		 BC010621 Gene ID (NCBI) 5830
Gene symbol PEX5 Synonyms FLJ50634, FLJ50721, FLJ51948, Peroxin 5, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1
Background PEX5抗体

The peroxisomal targeting signal type1 (PTS1) receptor, PEX5, is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins, respectively, and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic, partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10, PEX12, PEX13, and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS), which is a lethal peroxisome biogenesis disorder. This antibody recognizes endogenous PEX5, which migrates with an apparent molecular mass of 80 kDa (PMID: 7790377). PEX5抗体

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