重组人IGF-I (Animal Free)
产品名称： 重组人IGF-I (Animal Free)
英文名称： Recombinant Human IGF-I
产品编号： AF-100-11
产品价格： 0
产品产地： 美国PeproTech
品牌商标： 0
更新时间： null
使用范围： null
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重组人IGF-I (Animal Free) 1000ug详细介绍：
| 中文名称 | 重组人IGF-I (Animal Free) 1000ug详细介绍： |
| 英文名称 | Recombinant Human IGF-I |
| 货号 | AF-100-11 |
| 试剂级别 | 细胞培养级 |
| 产地 | 美国PeproTech |
| 别名Synonyms | Insulin-like Growth Factor-I, Somatamedin C, IGF-IA |
| 描述Description | The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. Manufactured using all non-animal reagents. |