PODS® Human BMP-4 人骨形态发生蛋白4
产品名称： PODS® Human BMP-4 人骨形态发生蛋白4
英文名称： PODS® Human BMP-4 (Bone morphogenetic protein 4)
产品编号： PPH56
产品价格： 0
产品产地： 英国
品牌商标： Cell Guidance Systems
更新时间： null
使用范围： null
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PODS® Human BMP-4
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 |
| PODS® co-crystals | PODS® co-crystals |
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CellGS Catalogue Code |
Product Name |
Pack Size |
|
|
PPH56-50 |
PODS Human BMP-4 |
50 million |
|
|
PPH56-250 |
PODS Human BMP-4 |
250 million |
|
|
PPH56-1000 |
PODS Human BMP-4 |
1 billion |
|
PODS 技术
将生长因子包埋进蛋白质晶体（多角体蛋白）中，多角体蛋白能够保护包埋的生长因子，并维持其稳定性与生物活性，进而持续释放到细胞培养系统中。
PODS BMP-4 描述
BMP (Bone morphogenetic protein,人骨形态发生蛋白) 是1963年美国的Marshall R.Urist教授发现的。骨形态发生蛋白能够诱导动物或人体间充质细胞分化为骨、软骨、韧带、肌腱和神经组织。
The product contains the polyhedrin protein co-crystalized with Human BMP-4. Bone Morphogenic Protein 4 (BMP-4) is a member of the Bone Morphogenetic Protein (BMP) family. These proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. BMP proteinsstimulate the production of bone matrix proteins and osteoclasts proliferation, and can be found on tissues related with bone or cartilage growth.
PODS BMP-4 规格
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PODS BMP-4 Product Details |
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Length |
452 aa |
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Molecular Weight |
103 kDa |
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Structure |
Dimer |
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Source |
Spodoptera frugiperda (Sf9) cell culture |
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Accession Number |
AAC72278.1 |
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Endotoxin Level |
<0.06 EU/ml as measured by gel clot LAL assay |
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Formulation |
PODS® were lyophilized from a volatile solution |
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Reconstitution |
PODS® co-crystals may be reconstituted at 200 million co-crystals/ml in water. 20% glucose has a buoyant density closer to PODS® co-crystals and can be useful for aliquoting. PODS® co-crystals are highly stable when stored in aqueous solution (pH range 6 - 8). |
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Stability and Storage |
Upon receipt, store at 4°C. PODS® co-crystals are stable for at least 1 year when dry and 6 months when resuspended. |
PODS GDNF 使用建议
PODS® co-crystals provide a depot of proteins which are steadily secreted. It has been estimated that the biological activity of 50 million PODS® co-crystals generates the same peak dose as 3.3 μg of standard recombinant protein. However, at 5 days following the start of seeding the PODS® co-crystals, there are more than 50% of these peak levels still present in the culture system. Ultimately, the amount of PODS® co-crystals that is optimal for a particular experiment should be determined empirically. Based on previous data, we suggest using 50 million PODS® co-crystals in place of 3.3 μg of standard growth factor as a starting point."
To control for cross-reactivity with cells or as a negative control, we recommend using PODS® growth factors alongside PODS® Empty crystals, as the latter do not contain or release cargo protein.
PODS BMP-4 AA Sequence
MADVAGTSNR DFRGREQRLF NSEQYNYNNS KNSRPSTSLY KKAGSIPGNR MLMVVLLCQV LLGGASHASL IPETGKKKVA EIQGHAGGRR SGQSHELLRD FEATLLQMFG LRRRPQPSKS AVIPDYMRDL YRLQSGEEEE EQIHSTGLEY PERPASRANT VRSFHHEEHL ENIPGTSENS AFRFLFNLSS IPENEAISSA ELRLFREQVD QGPDWERGFH RINIYEVMKP PAEVVPGHLI TRLLDTRLVH HNVTRWETFD VSPAVLRWTR EKQPNYGLAI EVTHLHQTRT HQGQHVRISR SLPQGSGNWA QLRPLLVTFG HDGRGHALTR RRRAKRSPKH HSQRARKKNK NCRRHSLYVD FSDVGWNDWI VAPPGYQAFY CHGDCPFPLA DHLNSTNHAI VQTLVNSVNS SIPKACCVPT ELSAISMLYL DEYDKVVLKN YQEMVVEGCG CR
PODS BMP-4 Alternative Names
Bone morphogenetic protein 4, bone morphogenetic protein 4A, BMP-4A, BMP4, BMP4A, 人骨形态发生蛋白4
PODS BMP-4 文件资料
 PPH56 Datasheet |
PODS User Guide |
PODS MSDS |
更多PODS 相关产品：PODS 生长因子
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