FITC标记的核转录因子YB抗体
产品名称： FITC标记的核转录因子YB抗体
英文名称： Anti-NFYB/FITC
产品编号： HZ-19230R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NFYB/FITC Conjugated antibody
FITC标记的核转录因子YB抗体
| 英文名称 | Anti-NFYB/FITC |
| 中文名称 | FITC标记的核转录因子YB抗体 |
| 别 名 | CAAT box DNA binding protein subunit B; CBF A; CBF B; CCAAT binding transcription factor subunit A; HAP 3; HAP3; NF Y protein chain B; NF YB; NFYB; Nuclear transcription factor Y beta; Nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Horse, Xenopus laevis. |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NFYB |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008] Function: Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. Subcellular Location: Nucleus. Similarity: Belongs to the NFYB/HAP3 subunit family. Database links: Entrez Gene: 396205 Chicken Entrez Gene: 614382 Cow Entrez Gene: 4801 Human Entrez Gene: 18045 Mouse Entrez Gene: 100157587 Pig Entrez Gene: 25336 Rat Entrez Gene: 399126 Xenopus laevis Omim: 189904 Human SwissProt: P25207 Chicken SwissProt: Q32KW0 Cow SwissProt: P25208 Human SwissProt: P63139 Mouse SwissProt: P63140 Rat SwissProt: Q5FVT0 Rat SwissProt: 100157587 Xenopus laevis SwissProt: P25211 Xenopus laevis Unigene: 84928 Human Unigene: 245998 Mouse Unigene: 90077 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白是三聚体复合物的一个亚基，形成高度保守的转录因子，与各种基因的启动子区域的CCAAT基序结合具有高度特异性。该基因产物亚基B与C亚基形成紧密的二聚体，是亚基A关联的先决条件。所得到的三聚体结合到具有高特异性和亲和力的DNA。Subunits B和C均含有组蛋白样基序。观察这些亚单位的组蛋白性质有两种证据：蛋白质序列比对和突变实验。[ RefSeq，JUL 2008 ]