INS (Human) Recombinant Protein (P01)
产品名称： INS (Human) Recombinant Protein (P01)
英文名称： INS (Human) Recombinant Protein (P01)
产品编号： H00003630-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human INS full-length ORF ( AAH05255.1, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
- Theoretical MW (kDa):
- 38.4
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3630
- GeneBank Accession#:
- BC005255.1
- Protein Accession#:
- AAH05255.1
- Gene Name:
- INS
- Gene Alias:
- ILPR,IRDN
- Gene Description:
- insulin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
- Other Designations:
- OTTHUMP00000011161,OTTHUMP00000011162,OTTHUMP00000196038,proinsulin
- Related Disease
- Addison Disease
- Adenomatous Polyps
- Alzheimer Disease
- Alzheimer disease
- Amenorrhea
- Anorexia Nervosa
- Atherosclerosis
- Autoimmune Diseases
- Autoimmune polyglandular syndrome
- Bile Duct Neoplasms
- Birth Weight
- Body Weight
- Breast cancer
- Breast Neoplasms
- Bulimia
- Carcinoma
- Carcinoma, Hepatocellular
- Cardiovascular Diseases
- Celiac Disease