FITC标记的酪氨酸磷酸酶受体相互作用蛋白Liprin α2抗体
产品名称： FITC标记的酪氨酸磷酸酶受体相互作用蛋白Liprin α2抗体
英文名称： Anti-Liprin alpha 2/FITC
产品编号： HZ-18299R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Liprin alpha 2/FITC Conjugated antibody
FITC标记的酪氨酸磷酸酶受体相互作用蛋白Liprin α2抗体
| 英文名称 | Anti-Liprin alpha 2/FITC |
| 中文名称 | FITC标记的酪氨酸磷酸酶受体相互作用蛋白Liprin α2抗体 |
| 别 名 | LIPA2_HUMAN; Liprin-alpha-2; PPFIA2; Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2; Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; PTPRF interacting protein alpha 2; PTPRF-interacting protein alpha-2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 信号转导 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 143kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Liprin alpha 2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Function: Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. Subcellular Location: Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface. Tissue Specificity: Expressed only in brain. Similarity: Belongs to the liprin family. Liprin-alpha subfamily. Contains 3 SAM (sterile alpha motif) domains. Database links: Entrez Gene: 8499 Human Omim: 603143 Human SwissProt: O75334 Human SwissProt: Q2M3G8 Human Unigene: 506216 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
由该基因编码的蛋白质是LAR蛋白酪氨酸磷酸酶相互作用蛋白（利普林）家族的成员。Liprins与跨膜蛋白酪氨酸磷酸酶LAR家族成员相互作用，已知LAR家族成员对轴突引导和乳腺发育很重要。已经提出，脂蛋白是形成复杂结构的多价蛋白质，并且作为LAR酪氨酸磷酸酶家族的募集和锚定的支架。这种蛋白已被证明与钙/钙调素依赖性丝氨酸蛋白激酶(MAGUK家族)蛋白(也称为CASK)结合，并被提议调节哺乳动物的高阶脑功能。选择性剪接导致多个转录变体。[ RefSeq，SEP 2013提供]