Recombinant Human VASN, His-tagged-蛋白质/抗原/多肽-试剂-生物在线
北京安必奇生物科技有限公司
Recombinant Human VASN, His-tagged

Recombinant Human VASN, His-tagged

商家询价

产品名称: Recombinant Human VASN, His-tagged

英文名称: Recombinant Human VASN, His-tagged

产品编号: VASN-8615H

产品价格: 0

产品产地: USA

品牌商标: Creative Biomart

更新时间: null

使用范围: null

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http://www.creativebiomart.net/description_382755_12.htm

Vasorin contains tandem arrays of a characteristic leucine-rich repeat motif, an epidermal growth factor-like motif, and a fibronectin type III-like motif at the extracellular domain. It is a type I membrane protein that is expressed predominantly in vascular Smooth muscle cells. Vasorin directly binds to TGF-beta and attenuates TGF-beta signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall. It may act as an inhibitor of TGF-beta signaling. Vasorin interacts with TGFB1, TGFB2 and TGFB3.