Recombinant Human VASN, His-tagged
产品名称: Recombinant Human VASN, His-tagged
英文名称: Recombinant Human VASN, His-tagged
产品编号: VASN-8615H
产品价格: 0
产品产地: USA
品牌商标: Creative Biomart
更新时间: null
使用范围: null
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Vasorin contains tandem arrays of a characteristic leucine-rich repeat motif, an epidermal growth factor-like motif, and a fibronectin type III-like motif at the extracellular domain. It is a type I membrane protein that is expressed predominantly in vascular Smooth muscle cells. Vasorin directly binds to TGF-beta and attenuates TGF-beta signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall. It may act as an inhibitor of TGF-beta signaling. Vasorin interacts with TGFB1, TGFB2 and TGFB3.