MTOR polyclonal antibody
产品名称： MTOR polyclonal antibody
英文名称： MTOR polyclonal antibody
产品编号： PAB12944
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of FRAP1.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 15 amino acids of human FRAP1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression.
Fingar DC, Blenis J.Oncogene. 2004 Apr 19;23(18):3151-71.
- 2.
- Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin.
Cardenas ME, Zhu D, Heitman J.Curr Opin Nephrol Hypertens. 1995 Nov;4(6):472-7.
- 3.
- RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH.Cell. 1994 Jul 15;78(1):35-43.
- Entrez GeneID:
- 2475
- Protein Accession#:
- NP_004949
- Gene Name:
- MTOR
- Gene Alias:
- FRAP,FRAP1,FRAP2,RAFT1,RAPT1
- Gene Description:
- mechanistic target of rapamycin
- Omim ID:
- 601231
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq
- Other Designations:
- FK506 binding protein 12-rapamycin associated protein 1,FK506 binding protein 12-rapamycin associated protein 2,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP-rapamycin associated protein,FKBP12-rapamycin complex-associated protein 1