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上海信裕生物科技有限公司
HHIP抗体

HHIP抗体

商家询价

产品名称： HHIP抗体

英文名称： HHIPAntibody

产品编号： XY11654-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 HHIP抗体

Applications
In-house applications ELISA, IHC, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 11654-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 11654-1-AP(HHIP antibody) at dilution of 1:1000
  • 11654-1-AP;Breast cancerImmunohistochemical of paraffin-embedded human breast cancer using 11654-1-AP(HHIP antibody) at dilution of 1:50 (under 10x lens)
Positive WB detected in HEK-293 cells, mouse heart tissue
Positive IHC detected in Human breast cancer tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
 HHIP抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen HHIP fusion protein ag2241 Full name Hedgehog interacting protein
Calculated molecular
weight		 700aa,79 kDa Observed molecular 
weight		 79 kDa
GenBank accession 
number		 BC025311 Gene ID (NCBI) 64399
Gene symbol HHIP Synonyms FLJ20992, FLJ90230, hedgehog interacting protein, HHIP, HIP
Background HHIP抗体

HHIP is a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height. HHIP抗体

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