TRIM5 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TRIM5 抗体

TRIM5 抗体

商家询价

产品名称: TRIM5 抗体

英文名称: TRIM5 Antibody

产品编号: XY 11476-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
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 TRIM5 抗体Applications

In-house applications ELISA, IHC, WB     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
Prev1NextView more validation data
  • 11476-1-AP;Prostate cancerImmunohistochemical of paraffin-embedded human prostate cancer using 11476-1-AP(TRIM5 antibody) at dilution of 1:50 (under 10x lens)
  • 11476-1-AP;MKN-45 cellsMKN-45 cells were subjected to SDS PAGE followed by western blot with 11476-1-AP( TRIM5 Antibody) at dilution of 1:300
Positive WB detected in MKN-45 cells, mouse stomach tissue
Positive IHC detected in Human prostate cancer tissue, human stomach tissue
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
 TRIM5 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information TRIM5 抗体
Immunogen TRIM5 fusion protein ag1973 Full name Tripartite motif-containing 5
Calculated molecular
weight
493aa,56 kDa Observed molecular 
weight
46 kDa, 70 kDa
GenBank accession 
number
BC021258 Gene ID (NCBI) 85363
Gene symbol TRIM5 Synonyms RING finger protein 88, RNF88, TRIM5, TRIM5alpha, tripartite motif containing 5
Background

TRIM5 belongs to the large tripartite motif protein family, members of which typically are composed of 3 zinc-binding domains, a RING, unique B-box type 1 and B-box type 2 domains, followed by a coiled-coil (CC) region. TRIM proteins use homomultimerization to identify specific cell compartments. TRIM5 promotes innate immune signaling and that this activity is amplified by retroviral infection and interaction with the capsid lattice. TRIM5 has 6 variants termed alpha, beta, gamma, delta, epsilon, and iota with the MW of 56 kDa, 46 kDa, 40 kDa, 37 kDa, 31 kDa and 29 kDa. TRIM5 can form homodimers (~70 kDa) and homotrimers (90-160 kDa). TRIM5 抗体

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