DAPK1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
DAPK1抗体

DAPK1抗体

商家询价

产品名称： DAPK1抗体

英文名称： DAPK1Antibody

产品编号： XY25136-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 DAPK1抗体

Applications
In-house applications ELISA, WB, IF     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 25136-1-AP;A549 cellsA549 cells were subjected to SDS PAGE followed by western blot with 25136-1-AP( DAPK1 Antibody) at dilution of 1:600
  • 25136-1-AP;A549 cellsImmunofluorescent analysis of A549 cells using 25136-1-AP( DAPK1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in A549 cells
Positive IF detected in A549 cells
Recommended dilution WB : 1:200-1:2000
IF : 1:50-1:500
 DAPK1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen DAPK1 fusion protein ag18387 Full name Death-associated protein kinase 1
Calculated molecular
weight		 1430aa,160 kDa Observed molecular 
weight		 140-160 kDa
GenBank accession 
number		 BC113660 Gene ID (NCBI) 1612
Gene symbol DAPK1 Synonyms DAP kinase 1, DAPK, DAPK1, DKFZp781I035
Background DAPK1抗体

DAPK1(Death-associated protein kinase 1) is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. Loss of DAPK1 expression is associated with a selective advantage fortumor cells to resist apoptotic stimuli, allowing them to separate from the original tumor; from this point of view, DAPK1 could be considered a tumor metastases inhibitor gene(PMID:17319784). This protein has 3 isoforms produced by alternative splicing. DAPK1抗体

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