重组人LEC/CCL16-RNAi技术-试剂-生物在线
上海沪震实业有限公司
重组人LEC/CCL16

重组人LEC/CCL16

商家询价

产品名称： 重组人LEC/CCL16

英文名称： Recombinant Human Liver-Expressed Chemokine/CCL16

产品编号： HZ4428

产品价格： 0

产品产地： 中国/上海

品牌商标： 沪震生物

更新时间： 2023-08-17T10:24:20

使用范围： null

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 重组人LEC/CCL16

中文名称：重组人LEC/CCL16
英文名称：Recombinant Human Liver-Expressed Chemokine/CCL16
产品规格：5μg
分子量：Approximately 11.2kDa,a single non-glycosylated polypeptide chain containing 97 amino acids.
储存条件：冷冻（-20℃）

概述

Human CCL16,also called Liver-expressed chemokine(LEC),Monotactin-1(MTN-1),IL-10-inducible chemokine and so on,is expressed by the CCL16 gene located on the chromosome 17 in humans.The gene encodes a 120 a.a.residue precursor protein with a 23 a.a.residue predicted signal peptide that is cleaved to generate a 97 a.a.residue mature protein.The protein is secreted by the liver,thymus,spleen cells and showing chemotactic activity for lymphocytes and monocytes but it is distantly related to other CC chemokines,exhibiting less than 30%sequence identity.CCL16 is highly induced by IL-10,IFN-γ and bacterial lipopolysaccharide in monmcytes and signal through CCR1,CCR2,CCR5,and CCR8.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观 Sterile Filtered White lyophilized(freeze-dried)powder.
纯度 ＞97%by SDS-PAGE and HPLC analyses.
来源 Escherichia coli.
生物活性 Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100ng/ml.
成分 Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl.
内毒素 Less than 1 EU/μg of rHuLEC/CCL16 as determined by LAL method.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列 QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ

 

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！