FITC标记的选择连接蛋白32抗体
产品名称： FITC标记的选择连接蛋白32抗体
英文名称： Anti-SNX32/FITC
产品编号： HZ-16118R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SNX32/FITC Conjugated antibody
FITC标记的选择连接蛋白32抗体
| 英文名称 | Anti-SNX32/FITC |
| 中文名称 | FITC标记的选择连接蛋白32抗体 |
| 别 名 | DKFZp761P1320; FLJ30934; MGC42112; MGC57276; SNX32; SNX32_HUMAN; SNX6B; Sortin nexin 32; Sortin nexin 6B; Sorting nexin-32; Sorting nexin-6B. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 46kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SNX32 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SNX32 is a 403 amino acid protein that contains one PX (phox homology) domain and belongs to the sorting nexin family. Existing as two alternatively spliced isoforms, SNX32 may be involved in several stages of intracellular trafficking. The gene that encodes SNX32 consists of approximately 23,256 bases and maps to human chromosome 11q13.1. Housing over 1,400 genes and comprising nearly 4% of the human genome, chromosome 11 is considered a gene and disease association-dense chromosome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. In addition, the blood disorders Sickle cell anemia and thalassemia are caused by mutations in the HBB gene, which is located on chromosome 11. Function: May be involved in several stages of intracellular trafficking. Similarity: Belongs to the sorting nexin family. Contains 1 PX (phox homology) domain. Database links: Entrez Gene: 254122 Human SwissProt: Q86XE0 Human Unigene: 591950 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
SNX32是一个含有一个PX（PHOX同源）结构域的403氨基酸蛋白，属于分类Nexin家族。Snx32作为两种交替剪接的亚型存在，可能参与细胞内运输的几个阶段。编码SNX32的基因由大约23256个碱基组成，并映射到人类染色体11q131。染色体11包含1400多个基因，占人类基因组的近4%，被认为是基因和疾病相关的致密染色体。Jervell和Lange-Nielsen综合征、Jac.n综合征、Niemann-Pick病、遗传性血管水肿和Smith-Lemli-Opitz综合征与映射到11号染色体的基因缺陷有关。此外，镰状细胞性贫血和地中海贫血是由位于11号染色体上的HBB基因突变引起的。