神经丝蛋白单克隆抗体
产品名称： 神经丝蛋白单克隆抗体
英文名称： AD7c-NTP
产品编号： hzm-36100M
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
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Mouse Anti-AD7c-NTP antibody
| 产品编号 | hzm-36100M |
| 英文名称 | AD7c-NTP |
| 中文名称 | 神经丝蛋白单克隆抗体 |
| 别 名 | neuronal thread protein AD7c-NTP; AD7c-NTP. |
| 研究领域 | 神经生物学 信号转导 细胞凋亡 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | 4E7 |
| 交叉反应 | Human, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 细胞定位 | 细胞浆 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Recombinant human AD7C NTP full length protein: |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein G |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease. SWISS: O60934 Gene ID: 4683 Database links: GenBank: AAC08737 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. AD7C-NTP是存在于神经元中的一种41Kda的蛋白质，在AD患者脑内选择性升高，和其病理过程相关，AD7C-NTP基因也只在神经元表达，AD患者脑脊液中AD7C-NTP表达升高， AD7C-NTP作为AD早期诊断和确诊的生物化学标志正引起越来越多的关注. |