FITC标记的淋巴细胞抗原6重复位点蛋白G6F抗体
产品名称： FITC标记的淋巴细胞抗原6重复位点蛋白G6F抗体
英文名称： Anti-LY6G6F/FITC
产品编号： HZ-20073R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LY6G6F/FITC Conjugated antibody
FITC标记的淋巴细胞抗原6重复位点蛋白G6F抗体
| 英文名称 | Anti-LY6G6F/FITC |
| 中文名称 | FITC标记的淋巴细胞抗原6重复位点蛋白G6F抗体 |
| 别 名 | C6orf21; Chromosome 6 open reading frame 21; G6F; G6f protein [Precursor]; HCG43720, isoform CRA_c; LY66F_HUMAN; LY6G6D; Ly6g6f; Lymphocyte antigen 6 complex locus G6F; Lymphocyte antigen 6 complex locus protein G6f; Lymphocyte antigen 6 complex, locus G6D; NG32. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from rat LY6G6F |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: lymphocyte antigen 6 complex locus protein G6f is a single-pass type I membrane protein belonging to the immunoglobulin (Ig) superfamily. Located in the class III region of the major histocompatibility complex (MHC), the G6f gene lies in a cluster of genes encoding cell-surface proteins that play a role in the immune system and cellular recognition. G6f functions as a downstream effector of GRB2 and GRB7, and, in humans, it interacts with GRB2 and GRB7 through the phosphorylation of a tyrosine residue (Tyr 281) in the intracellular tail of G6f. This interaction is also mediated by the SH2 domain of GRB2 and possibly that of GRB7. G6f is a 297 amino acid protein, and it forms a disulfide-linked homodimer. Function: May play a role in the downstream signal transduction pathways involving GRB2 and GRB7. Subcellular Location: Cell membrane. Post-translational modifications: modificationsN-glycosylated. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. Database links: Entrez Gene: 259215 Human Entrez Gene: 309609 Rat Entrez Gene: 433099 Mouse Omim: 611404 Human SwissProt: Q5SQ64 Human SwissProt: Q7Z5H2 Human SwissProt: Q6MG56 Rat Unigene: 591794 Human Unigene: 145028 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
淋巴细胞抗原6复合位点蛋白G6f是属于免疫球蛋白（Ig）超家族的单程I型膜蛋白。G6f基因位于主要组织相容性复合体（MHC）的第III类区域，位于编码细胞表面蛋白的基因簇中，在免疫系统和细胞识别中发挥作用。G6f是GRB2和GRB7的下游效应子，在人类中，它通过G6f胞内尾部酪氨酸残基(Tyr 281)的磷酸化与GRB2和GRB7相互作用。G6F是一个297氨基酸的蛋白质，并形成二硫键连接的同型二聚体。