RUNX2/CEN6p FISH Probe-核酸检测-试剂-生物在线
亚诺法生技股份有限公司（Abnova)
RUNX2/CEN6p FISH Probe

RUNX2/CEN6p FISH Probe

商家询价

产品名称： RUNX2/CEN6p FISH Probe

英文名称： RUNX2/CEN6p FISH Probe

产品编号： FG0031

产品价格： 0

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围： null

亚诺法生技股份有限公司（Abnova)
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  • 所在区域 : 台湾
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0031
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Note:

  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • RUNX2
    Approximately 230kb
    Texas Red
    6p21
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN6p
    Approximately 660kb
    FITC
    6p12.1
  • Probe Gap:
  • The gap between two probes is approximately 2,800 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human breast carcinoma (FFPE) stained with RUNX2/CEN6p FISH Probe. Human breast carcinoma showed RUNX2 gene amplification (RUNX2/CEN6p ratio ≥ 2).
  • Protocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 860
  • Gene Name:
  • RUNX2
  • Gene Alias:
  • AML3,CBFA1,CCD,CCD1,MGC120022,MGC120023,OSF2,PEA2aA,PEBP2A1,PEBP2A2,PEBP2aA,PEBP2aA1
  • Gene Description:
  • runt-related transcription factor 2
  • Gene Summary:
  • This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq
  • Other Designations:
  • CBF-alpha 1,OTTHUMP00000016533,SL3-3 enhancer factor 1 alpha A subunit,SL3/AKV core-binding factor alpha A subunit,acute myeloid leukemia 3 protein,core-binding factor, runt domain, alpha subunit 1,osteoblast-specific transcription factor 2,polyomavirus e

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