DGKK,甘油二酯激酶κ/DGK-κ抗体

产品编号HZ-14300R
英文名称DGKK
中文名称甘油二酯激酶κ/DGK-κ抗体
别 名142 kDa diacylglycerol kinase; DAG kinase kappa; DGK kappa; DGKK_HUMAN; Diacylglycerol kinase kappa; Diglyceride kinase kappa.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
DGKK,甘油二酯激酶κ/DGK-κ抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量142kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DGKK
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DGKK,甘油二酯激酶κ/DGK-κ抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]

Function:
DGKK (Diacylglycerol kinase kappa) phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).

Subunit:
Does not form homooligomers.

Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein

Tissue Specificity:
Expressed in testis, and to a lesser extent in placenta.

Post-translational modifications:
Phosphorylated at Tyr-78 by some member of the SRC family in response to H(2)O(2).

DGKK,甘油二酯激酶κ/DGK-κ抗体Similarity:
Belongs to the eukaryotic diacylglycerol kinase family.
Contains 1 DAGKc domain.
Contains 1 PH domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.

Gene ID:
139189

Database links:
Entrez Gene: 139189 Human
Entrez Gene: 331374 Mouse
SwissProt: Q5KSL6 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.