EXOC7,EXOC7蛋白抗体

产品编号HZ-14664R
英文名称EXOC7
中文名称EXOC7蛋白抗体
别 名2 5 3p; DKFZp686J04253; EX070; EXO70; Exo70p; EXOC 1; EXOC 7; EXOC1; Exoc7; EXOC7_HUMAN; Exocyst complex component 7; Exocyst complex component Exo70; FLJ40965; FLJ46415; KIAA1067; Rexo70; YJL085W.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 转运蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit,
EXOC7,EXOC7蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量83kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EXOC7
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EXOC7,EXOC7蛋白抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]

Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion.

Subunit:

Subcellular Location:
Cytoplasm > cytosol. Cell membrane. Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ.

Similarity:
Belongs to the EXO70 family.

Gene ID:
23265

EXOC7,EXOC7蛋白抗体Database links:
Entrez Gene: 23265 Human
Entrez Gene: 417361 Chicken
Entrez Gene: 505568 Cow
Entrez Gene: 53413 Mouse
Entrez Gene: 64632 Rat
Entrez Gene: 406723 Zebrafish
Omim: 608163 Human
SwissProt: Q5ZIN3 Chicken
SwissProt: Q3ZC43 Cow
SwissProt: Q9UPT5 Human
SwissProt: O35250 Mouse
SwissProt: O54922 Rat
SwissProt: Q7ZTX5 Zebrafish
Unigene: 514496 Human
Unigene: 533985 Human
Unigene: 22530 Mouse
Unigene: 45761 Rat

EXOC7,EXOC7蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.