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上海信裕生物科技有限公司
Emerin抗体

Emerin抗体

商家询价

产品名称： Emerin抗体

英文名称： EmerinAntibody

产品编号： XY10351-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 EMERIN抗体

Applications
In-house applications ELISA, WB, IP, IF, FC     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
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  • 10351-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 10351-1-AP(EMD antibody) at dilution of 1:1000
  • 10351-1-AP;mouse skeletal muscle tissueIP result of EMD antibody (10351-1-AP for IP and Detection) with mouse skeletal muscle tissue lysate.
  • 10351-1-AP;HeLa cellsIF result of anti-EMD(10351-1-AP) in Hela cell by Dr. Ralph Kehlenbach.
  • 10351-1-AP;Hela cellsImmunofluorescent analysis of Hela cells, using EMD antibody 10351-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 10351-1-AP;HEK-293T cells1X10^6 HEK-293T cells were stained with 0.2ug EMD antibody (10351-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.
Positive WB detected in HeLa cells, A431 cells, COLO 320 cells, HEK-293 cells, HepG2 cells, Jurkat cells, MCF7 cells
Positive IP detected in Mouse skeletal muscle tissue
Positive IF detected in Hela cells, A431 cells, MCF-7 cells
Positive FC detected in HEK-293T cells
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IF : 1:10-1:100
 EMERIN抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information EMERIN抗体
Immunogen Emerin fusion protein ag0236 Full name Emerin
Calculated molecular
weight		 29 kDa Observed molecular 
weight		 35kd
GenBank accession 
number		 BC000738 Gene ID (NCBI) 2010
Gene symbol EMD Synonyms EDMD, EMD, Emerin, LEMD5, STA
Background

Emerin (Emery-Dreifuss muscular dystrophy) (EMD or EDMD), a serine-rich nuclear membrane protein, is a member of the nuclear lamina-associated protein family. EMD may mediate membrane anchorage to the cytoskeleton by stabilizing and promoting the formation of a nuclear actin cortical network. Defects in EMD gene are the cause of Emery-Dreifuss muscular dystrophy type 1 (EDMD1), a degenerative myopathy characterized by weakness and atrophy of muscle without involvement of the nervous system, early contractures of the elbows Achilles tendons and spine, and cardiomyopathy associated with cardiac conduction defects. EMD inhibits beta-catenin activity by preventing its accumulation in the nucleus and is involved in HIV-1 infection. EMERIN抗体

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