PTGER3 Pre-design Chimera RNAi
产品名称： PTGER3 Pre-design Chimera RNAi
英文名称： PTGER3 Pre-design Chimera RNAi
产品编号： H00005733-R11
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Homo sapiens prostaglandin E receptor 3 (subtype EP3) (PTGER3), transcript variant 1, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000957
- Target Region:
- Coding sequence
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 5733
- Gene Name:
- PTGER3
- Gene Alias:
- EP3,EP3-I,EP3-II,EP3-III,EP3-IV,EP3e,MGC141828,MGC141829,MGC27302
- Gene Description:
- prostaglandin E receptor 3 (subtype EP3)
- Omim ID:
- 176806
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000011033,OTTHUMP00000011034,OTTHUMP00000011035,PGE receptor, EP3 subtype,prostaglandin E receotor EP3 subtype 3 isoform,prostaglandin E receptor 3, subtype EP3,prostaglandin E2 receptor,prostaglandin receptor (PGE-2),prostanoid EP3 receptor
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Asthma
- Asthma
- Cardiovascular Diseases
- Chorioamnionitis
- Connective Tissue Diseases
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Edema
- Fetal Diseases
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Infection
- Inflammation
- Kidney Failure, Chronic
- Metabolic Syndrome X
- Musculoskeletal Diseases
- Neoplasms