NOGO Antibody
产品名称: NOGO Antibody
英文名称: NOGO Antibody
产品编号: 251677
产品价格: null
产品产地: 美国
品牌商标: Abbiotec
更新时间: null
使用范围: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
深圳市豪地华拓生物科技有限公司
- 联系人 :
- 地址 : 深圳市南山创业路中兴城5栋518
- 邮编 : 518054
- 所在区域 : 广东
- 电话 : 132****4656 点击查看
- 传真 : 点击查看
- 邮箱 : order@otwobiotech.com
Neurite outgrowth inhibitor (NOGO) plays a role both in the restriction of axonal regeneration after injury and in structural plasticity in the CNS. Isoform 2 of NOGO reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 of NOGO inhibit BACE1 activity and amyloid precursor protein processing.