FITC标记的细胞骨架相关蛋白抗体
产品名称: FITC标记的细胞骨架相关蛋白抗体
英文名称: Anti-SM22 Alpha/FITC
产品编号: HZ-2178R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SM22 Alpha/FITC Conjugated antibody
FITC标记的细胞骨架相关蛋白抗体
英文名称 | Anti-SM22 Alpha/FITC |
中文名称 | FITC标记的细胞骨架相关蛋白抗体 |
别 名 | 22 kDa actin binding protein; 22 kDa actin-binding protein; Transgelin; DKFZp686P11128; Human 22kDa smooth muscle protein; Protein WS3-10; SM22 alpha; SM22; SM22-alpha; SMCC; Smooth muscle protein 22-alpha; TAGL_HUMAN; TAGLN; TAGLN1; transgelin; Transgelin variant 2; WS3 10; Protein WS3-10; WS3-10. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 心血管 细胞生物 信号转导 细胞骨架 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SM22 Alpha |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Function: Actin cross-linking/gelling protein. Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. Subcellular Location: Cytoplasm (Probable). Similarity: Belongs to the calponin family. Contains 1 calponin-like repeat. Contains 1 CH (calponin-homology) domain. Database links: Entrez Gene: 513463 Cow Entrez Gene: 6876 Human Entrez Gene: 8407 Human Entrez Gene: 21345 Mouse Entrez Gene: 25123 Rat Omim: 600818 Human SwissProt: Q9TS87 Cow SwissProt: Q01995 Human SwissProt: P37804 Mouse SwissProt: P31232 Rat Unigene: 410977 Human Unigene: 666842 Human Unigene: 283283 Mouse Unigene: 34397 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. SM22α蛋白是一种细胞骨架相关蛋白. |
由该基因编码的蛋白质是在成纤维细胞和平滑肌中发现的转化和形状变化敏感的肌动蛋白交联/胶凝蛋白。它的表达在许多细胞系中下调,这种下调可能是转化开始的一个早期和敏感的标志物。这种蛋白质的功能作用尚不清楚。已经发现了两个编码相同蛋白的转录变体。[ RefSeq,JUL 2008 ]