IL12A (Human) Recombinant Protein (Q01)
产品名称： IL12A (Human) Recombinant Protein (Q01)
英文名称： IL12A (Human) Recombinant Protein (Q01)
产品编号： H00003592-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human IL12A partial ORF ( NP_000873.2, 144 a.a. - 253 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- CLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS
- Theoretical MW (kDa):
- 37.62
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3592
- GeneBank Accession#:
- NM_000882
- Protein Accession#:
- NP_000873.2
- Gene Name:
- IL12A
- Gene Alias:
- CLMF,IL-12A,NFSK,NKSF1,P35
- Gene Description:
- interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- Omim ID:
- 161560
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq
- Other Designations:
- IL-12, subunit p35,NF cell stimulatory factor chain 1,cytotoxic lymphocyte maturation factor 1, p35,interleukin 12, p35,interleukin 12A,interleukin-12 alpha chain,natural killer cell stimulatory factor 1, 35 kD subunit
- Related Disease
- Abortion, Habitual
- Acquired Immunodeficiency Syndrome
- Adenocarcinoma
- Alveolitis, Extrinsic Allergic
- Alzheimer Disease
- Anemia
- Arthritis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Autoimmune Diseases
- Breast Neoplasms
- Bronchiolitis, Viral
- Bronchopulmonary Dysplasia
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Celiac Disease