Anti-KCNK9/FITC Conjugated抗体
产品名称: Anti-KCNK9/FITC Conjugated抗体
英文名称: Anti-KCNK9/FITC
产品编号: YB--5933R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
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Anti-KCNK9/FITC Conjugated抗体
产品编号 | YB-5933R-FITC |
英文名称 | Anti-KCNK9/FITC |
中文名称 | FITC标记的TWIK相关酸敏感钾离子通道蛋白9抗体 |
别 名 | KCNK 9; KCNK-9; TASK3; Potassium channel subfamily K member 9; Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Short=Two pore K(+) channel KT3.2; KCNK9_HUMAN |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 免疫学 神经生物学 通道蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KCNK9 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents. Function: pH-dependent, voltage-insensitive, background potassium channel protein. Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung. DISEASE: Defects in KCNK9 are the cause of Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:612292]. A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism. Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) Database links: Entrez Gene: 428382 Chicken Entrez Gene: 51305 Human Omim: 605874 Human SwissProt: Q9NPC2 Human Unigene: 493037 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |