EPHX1 monoclonal antibody, clone AT2E5
产品名称： EPHX1 monoclonal antibody, clone AT2E5
英文名称： EPHX1 monoclonal antibody, clone AT2E5
产品编号： MAB3588
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant EPHX1.
- Immunogen:
- Recombinant protein corresponding to amino acids 21-455 of human EPHX1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis.
van Loo B, Kingma J, Arand M, Wubbolts MG, Janssen DB.Appl Environ Microbiol. 2006 Apr;72(4):2905-17.
- 2.
- Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
Coller JK, Fritz P, Zanger UM, Siegle I, Eichelbaum M, Kroemer HK, Murdter TE.Histochem J. 2001 Jun;33(6):329-36.
- 3.
- The human microsomal epoxide hydrolase gene (EPHX1): complete nucleotide sequence and structural characterization.
Hassett C, Robinson KB, Beck NB, Omiecinski CJ.Genomics. 1994 Sep 15;23(2):433-42.
- Applications
- Western Blot (Tissue lysate)
- The extracts of mouse liver (30 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with EPHX1 monoclonal antibody, clone AT2E5 (Cat # MAB3588 ; 1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 2052
- Protein Accession#:
- NP_000111
- Gene Name:
- EPHX1
- Gene Alias:
- EPHX,EPOX,MEH
- Gene Description:
- epoxide hydrolase 1, microsomal (xenobiotic)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene
- Other Designations:
- OTTHUMP00000035867,epoxide hydratase,epoxide hydrolase 1,microsomal epoxide hydrolase
- Gene Pathway
- Related Disease