SCARB2 polyclonal antibody
产品名称： SCARB2 polyclonal antibody
英文名称： SCARB2 polyclonal antibody
产品编号： PAB13376
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SCARB2.
- Immunogen:
- A synthetic peptide corresponding to internal region 16 amino acids of human SCARB2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis.
Knipper M, Claussen C, Ruttiger L, Zimmermann U, Lullmann-Rauch R, Eskelinen EL, Schroder J, Schwake M, Saftig P.J Physiol. 2006 Oct 1;576(Pt 1):73-86. Epub 2006 Aug 10.
- 2.
- LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice.
Gamp AC, Tanaka Y, Lullmann-Rauch R, Wittke D, D'Hooge R, De Deyn PP, Moser T, Maier H, Hartmann D, Reiss K, Illert AL, von Figura K, Saftig P.Hum Mol Genet. 2003 Mar 15;12(6):631-46.
- 3.
- Isolation and sequencing of a cDNA clone encoding 85kDa sialoglycoprotein in rat liver lysosomal membranes.
Fujita H, Ezaki J, Noguchi Y, Kono A, Himeno M, Kato K.Biochem Biophys Res Commun. 1991 Jul 31;178(2):444-52.
- Entrez GeneID:
- 950
- Protein Accession#:
- AAH21892
- Gene Name:
- SCARB2
- Gene Alias:
- AMRF,CD36L2,HLGP85,LIMPII,SR-BII
- Gene Description:
- scavenger receptor class B, member 2
- Omim ID:
- 602257
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Studies of the similar protein in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. Deficiency of the similar protein in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. [provided by RefSeq
- Other Designations:
- 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2,CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II),lysosomal integral membrane protein II
- Gene Pathway