FITC标记的脂多糖相关反应蛋白5/γ-taxilin抗体
产品名称： FITC标记的脂多糖相关反应蛋白5/γ-taxilin抗体
英文名称： Anti-Gamma-taxilin/FITC
产品编号： HZ-0631R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Gamma-taxilin/FITC Conjugated antibody
FITC标记的脂多糖相关反应蛋白5/γ-taxilin抗体
| 产品编号 | bs-0631R-FITC |
| 英文名称 | Anti-Gamma-taxilin/FITC |
| 中文名称 | FITC标记的脂多糖相关反应蛋白5/γ-taxilin抗体 |
| 别 名 | chromosome X open reading frame 15; LSR5; CXorf15; Environmental lipopolysaccharide-responding gene protein; factor inhibiting activating transcription factor 4 (ATF4)-mediated transcription; Factor inhibiting ATF4-mediated transcription antibody FIAT; Gamma-taxilin; Lipopolysaccharide-specific response protein 5; LSR5; TXLNG; TXLNG_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 干细胞 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Gamma-taxilin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]. Function: May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression. Subunit: Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A. Forms a heterodimer with ATF4 in osteoblasts. Subcellular Location: Nucleus membrane. Cytoplasm, cytosol. Tissue Specificity: Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas. Similarity: Belongs to the taxilin family. Database links: Entrez Gene: 353170 Mouse SwissProt: Q8BHN1 Mouse Unigene: 270186 Mouse Unigene: 371732 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码紫杉醇家族的一员。编码的蛋白与突触结合蛋白家族成员1A、3A和4A的C-末端卷曲区结合，并可能在细胞内囊泡运输中起作用。该基因受脂多糖上调，基因产物可能参与细胞周期调控。相关的小鼠蛋白也显示抑制转录因子4-介导的转录，从而调节骨量增加。另一种编码不同的异构体的剪接转录变体已被发现用于该基因。[ RefSeq，DEC 2009 ]提供。