FITC标记的鸡传染性法氏囊病病毒抗体
产品名称： FITC标记的鸡传染性法氏囊病病毒抗体
英文名称： Anti-IBDV/FITC
产品编号： HZ-10050R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-IBDV/FITC Conjugated antibody
FITC标记的鸡传染性法氏囊病病毒抗体
| 英文名称 | Anti-IBDV/FITC |
| 中文名称 | FITC标记的鸡传染性法氏囊病病毒抗体 |
| 别 名 | Infectious Bursal Disease Vaccine; Infectious Bursal Disease virus; infectious bursal disease; IBD. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 细菌及病毒 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Infectious Bursal Disease virus |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Infectious Bursal Disease Vaccine |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Infectious bursal disease (also known as IBD, Gumboro Disease, Infectious Bursitis and Infectious Avian Nephrosis) is a highly contagious disease of young chickens caused by infectious bursal disease virus (IBDV), characterized by immunosuppression and mortality generally at 3 to 6 weeks of age. IBDV is a double stranded RNA virus that has a bi-segmented genome and belongs to the genus Avibirnavirus of family Birnaviridae. There are two distinct serotypes of the virus, but only serotype 1 viruses cause disease in poultry. At least six antigenic subtypes of IBDV serotype 1 have been identified by in vitro cross-neutralization assay. Viruses belonging to one of these antigenic subtypes are commonly known as variants, which were reported to break through high levels of maternal antibodies in commercial flocks, causing up to 60 to 100 percent mortality rates in chickens. With the advent of highly sensitive molecular techniques, such as reverse transcription polymerase chain reaction (RT-PCR) and restriction fragment length polymorphism (RFLP), it became possible to detect the vvIBDV, to differentiate IBDV strains, and to use such information in studying the molecular epidemiology of the virus. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 由双链RNA病毒科的传染性法氏囊病病毒(IBDV)所引起的一种鸡的急性暴发性传染病。表现为法氏囊淋巴组织和淋巴细胞坏死，发病率及死亡率均高。耐过鸡的法氏囊组织受损，导致免疫抑制，影响其他疫苗的免疫效果，常造成免疫失败。 IBDV的自然宿主仅为雏鸡和火鸡。从鸡分离的IBDV只感染鸡，感染火鸡不发病，但能引起抗体产生。同样，从火鸡分离的病毒仅能使火鸡感染，而不感染鸡。不同品种的鸡均有易感性。IBD母源抗体阴性的鸡可于1周龄内感染发病，有母源抗体的鸡多在母源抗体下降至较低水平时感染发病。3～6周龄的鸡最易感。也有15周龄以上鸡发病的报道。该病全年均可发生，无明显季节性。 病鸡的粪便中含有大量病毒，病鸡是主要传染源。鸡可通过直接接触和污染了IBDV的饲料、饮水、垫料、尘埃、用具、车辆、人员、衣物等间接传播，老鼠和甲虫等也可间接传播。有人从蚊子体内分离出一株病毒，被认为是一株IBDV自然弱毒，由此说明媒介昆虫可能参与该病的传播。该病毒不仅可通过消化道和呼吸道感染，还可通过污染了病毒的蛋壳传播，但未有证据表明经卵传播。另外，经眼结膜也可传播 |
传染性法氏囊病(也称为IBD、Gumboro病、传染性法氏囊炎和感染性禽肾病)是由传染性法氏囊病病毒(IBDV)引起的雏鸡的一种高度传染性疾病，其特点是免疫抑制和死亡率一般在3-6周龄。IBDV是一种双链RNA病毒，具有双片段基因组，属于Birnaviridae家族的禽流感病毒属。病毒有两种截然不同的血清型，但只有1型病毒引起家禽疾病。通过体外交叉中和试验鉴定了至少六种IBDV血清型1个抗原亚型。属于这些抗原亚型之一的病毒通常被称为变体，据报道，它们突破了商业鸡群中高水平的母体抗体，导致鸡高达60%至100%的死亡率。随着反转录聚合酶链反应（RT-PCR）和限制性片段长度多态性（RFLP）等高灵敏分子技术的出现，检测VvIBDV、鉴别IBDV毒株、以及利用这些信息研究分子成为可能。病毒的AR流行病学。