RCC1 (NM_001269) Human Recombinant Protein
产品名称: RCC1 (NM_001269) Human Recombinant Protein
英文名称: RCC1 (NM_001269) Human Recombinant Protein
产品编号: PH34361M5
产品价格: 0
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: null
安诺伦(北京)生物科技有限公司
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产品概述:Recombinant protein of human regulator of chromosome condensation 1 (RCC1), transcript variant 3 蛋白长度:Recombinant protein was produced with GoldORF clone, [GH51067V]. Click on the GoldORF clone link to view cDNA and protein sequences. 表达系统:HEK293T 种属:Human 标签类型:C-Myc/DDK 分子量:44.8 kDa 通用名:RCC1 总结:Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).[UniProtKB/Swiss-Prot Function] 形式:Liquid 浓度:>50 ug/mL as determined by microplate BCA method 纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol 别名:CHC1; RCC1-I; SNHG3-RCC1